Abstract. BELLO, Ariel et al. Splenic marginal zone lymphoma. Acta Med Colomb [online]. , vol, n.1, pp ISSN Non-Hodgkin. Splenic marginal zone lymphoma is a rare, indolent B-cell non-Hodgkin lymphoma characterized by abnormal clonal proliferation of mature B- lymphocytes with. Monoterapia com rituximab no linfoma da zona marginal esplênico com linfócitos vilosos: relato de dois casos de pacientes com controle prolongado da doença.

Author: Faejin Sharg
Country: Denmark
Language: English (Spanish)
Genre: Finance
Published (Last): 8 October 2008
Pages: 312
PDF File Size: 1.65 Mb
ePub File Size: 1.89 Mb
ISBN: 551-8-80092-514-7
Downloads: 6321
Price: Free* [*Free Regsitration Required]
Uploader: Taugami

Pemphigus Vegetans in the Inguinal Folds.

Orphanet: Linfoma esplenico de la zona marginal

In the year has been indexed in the Medlinedatabase, and has become a vehicle for expressing the most current Spanish medicine and modern. Unmutated immunoglobulin fsplenico heavy-chain gene status remains an adverse prognostic factor after autologous stem cell transplantation for chronic lymphocytic leukemia. CiteScore measures average citations received per document published. The treatment was well tolerated.

Our data show that pentostatin administered every other week has a good degree of activity in the treatment of SMZL and suggest that this schedule could be considered a possible therapeutic option for patients who are not fit for splenectomy or have relapsed. The median age was 64 years.

  ASME PVHO-1-2007 PDF

Median follow-up time for the entire series was At this time, the patient was referred to our center, and we decided to avoid chemotherapy and start rituximab as a single agent, because she presented with a creatinine level slightly over the normal range. Cytogenetic studies in seventy-six cases of B-chronic lymphoproliferative disorders. Splenic marginal zone lymphoma: The category of diffuse large B-cell lymphoma is heterogeneous, including several subtypes.

LEZM – Linfoma Esplénico de la Zona Marginal

The present case indicates that treatment with fludarabine is effective for SLVL and recommended as the first-line therapy for elderly patients and those with an aggressive form of the msrginal. Using these 3 variables, we grouped patients into 3 prognostic categories: Splenectomy confirmed the diagnosis of splenic MZL and led to resolution of the skin lesions. Pueden registrarse remisiones prolongadas en los tumores de bajo grado.

Intrasinusoidal bone marrow infiltration: In order to make our search as wide as possible, we did not apply any limits regarding the date of publication, the language ds or the type of article. The median clinical remission interval was 46 months.


There are no specific treatment guidelines for patients for whom splenectomy fails to provide a cure. Puede estar infiltrada la medula pero con buena reserva medular.

Detailed information Professionals Review article Deutsch However, a few patients relapse and the second-line treatment remains questionable. It needs to be emphasized that the evidence to support this approach is based only on case reports, since there are no randomized clinical trials on this subject.


September 27, Conflict of interest: Treatment of splenic marginal zone lymphoma: Maria alle Scotte, and University of Siena, Italy. Rituximab monotherapy for splenic marginal zone lymphoma. Continuing navigation will be considered as acceptance of this use.

lihfoma Furthermore it could constitute an alternative to splenectomy in older patients. The bone marrow was not compromised. The histopathology of splenic lymphoma with villous lymphocytes.

Therapy was well tolerated. Only comments written in English can be processed. Deleciones de 13q14, distales al gen de retinoblastoma.